APPROVED USE FOR MOVANTIK
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MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.

FAQs

Frequently asked questions

Opioid-induced constipation
What is opioid-induced constipation?

Opioids are prescription medicines like codeine, hydrocodone, morphine, oxycodone, fentanyl, and tramadol that are used to treat pain. Opioid-induced constipation is one of the most common side effects of opioid use.1-3

Opioids block pain signals by attaching to something called mu-receptors in the brain and other parts of the central nervous system. However, opioids also attach to mu-receptors in the bowel, which can cause opioid-induced constipation.4

MOVANTIK
What is MOVANTIK and who is it for?

MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.5

MOVANTIK—one pill once a day—is specifically designed for OIC in adults with chronic non-cancer pain. It works by blocking opioids from binding to something called mu-receptors in your bowel.5

How long does it take for MOVANTIK to work?

In clinical studies, MOVANTIK worked quickly, often within 6 to 12 hours of the first dose.5

How is MOVANTIK different from many other treatments for constipation?

MOVANTIK is a prescription medicine specifically designed to relieve constipation caused by opioid treatment in adults with long-lasting (chronic) pain that is not caused by active cancer.5

Will taking MOVANTIK change the way I take my opioid pain medication?

When starting MOVANTIK, changes to your opioid dosing regimen are not required. It’s important to talk to your doctor about your pain management and opioid dose.5

What are the possible side effects of MOVANTIK?

MOVANTIK may cause serious side effects, including5:

Opioid withdrawal.

  • You may have symptoms of opioid withdrawal during treatment with MOVANTIK including sweating, chills, diarrhea, stomach pain, anxiety, irritability, and yawning. If you take methadone to treat your pain, you may be more likely to have stomach pain and diarrhea than people who do not take methadone. Tell your health care provider if you have any of these symptoms

Severe stomach pain or diarrhea, or both severe stomach pain and diarrhea.

  • Severe stomach pain and diarrhea can happen when you take MOVANTIK. These problems can happen within a few days after you start taking MOVANTIK and can lead to hospitalization. Stop taking MOVANTIK and call your healthcare provider right away if you have severe stomach pain or diarrhea, or both severe stomach pain and diarrhea

Tear in your stomach or intestinal wall (perforation).

  • Stomach pain that is severe can be a sign of a serious medical condition. If you have stomach pain that gets worse or does not go away, stop taking MOVANTIK and get emergency medical help right away

The most common side effects of MOVANTIK include: stomach (abdomen) pain, diarrhea, nausea, gas, vomiting, and headache.5

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of MOVANTIK.

Call your doctor for medical advice about side effects.

Please see Important Safety Information, Medication Guide, and US Full Prescribing Information.

How should I take MOVANTIK?

You should take MOVANTIK exactly as your health care provider tells you. Be sure to take your prescribed dose of MOVANTIK 1 time each day, on an empty stomach, at least 1 hour before your first meal of the day or 2 hours after the meal. You should also stop taking other laxatives before you start treatment with MOVANTIK. Your health care provider may prescribe other laxatives if MOVANTIK does not work after 3 days of treatment.5

Where can I find the MOVANTIK Prescribing Information?
Savings and coverage
Is MOVANTIK covered by insurance?

The majority of commercial patients* nationwide are covered for MOVANTIK.* Ask your pharmacist or check with your insurance provider.6

*“Patients” means covered lives (Commercial, Commercial [BCBS], Employer, Federal Employees Health Benefit Plans [FEHBPs], Federal Programs, Municipal Plan, Pharmacy Benefit Manager [PBM], Union) at Tiers 1-7 and the $0 Co-pay tier in the region, as calculated by Managed Markets Insight & Technology, LLC database as of June 24, 2020.
“Covered” means any coverage level, specifically Tiers 1-7 and the $0 Co-pay tier, regardless of restrictions.
How much does MOVANTIK cost?

With the savings card, eligible patients pay as little as $0 per month for MOVANTIK. That’s less than the cost of over-the-counter laxatives.*6

*Over-the-counter laxatives include Colace®, Dulcolax®, ex-lax®, MiraLAX®, Peri-Colace®, Senokot®, and Senokot-S®.7
Pricing comparisons do not imply comparable efficacy, safety, or FDA-approved indications.
Product names are registered trademarks of their respective owners.

ELIGIBILITY:
You may be eligible for this offer if you are insured by commercial insurance and your insurance does not cover the full cost of your prescription, or you are not insured and are responsible for the cost of your prescriptions.

Patients who are enrolled in a state or federally funded prescription insurance program are not eligible for this offer. This includes patients enrolled in Medicare Part D, Medicaid, Medigap, Veterans Affairs (VA), Department of Defense (DOD) programs or TriCare, and patients who are Medicare eligible and enrolled in an employer-sponsored group waiver health plan or government-subsidized prescription drug benefit program for retirees.

If you are enrolled in a state or federally funded prescription insurance program, you may not use this Savings Card even if you elect to be processed as an uninsured (cash-paying) patient.

This offer is not insurance and is restricted to residents of the United States and Puerto Rico and patients over 18 years of age. This offer is valid for retail prescriptions only.

TERMS OF USE:
Eligible commercially insured patients with a valid prescription for MOVANTIK® (naloxegol) tablets who present this Savings Card at participating pharmacies will pay $0 per 30-day supply, subject to a maximum savings of $100 per 30-day supply. Cash-paying patients will receive up to $100 in savings on out-of-pocket costs that exceed $0 per 30-day supply. This offer is good for 12 uses and each 30-day supply counts as 1 use. Other restrictions may apply. Patient is responsible for applicable taxes, if any. If you have any questions regarding this offer, please call 844-4-MOVSAVE.

Offer expires on 12/31/2021.

Non-transferable, limited to one per person, cannot be combined with any other offer. Void where prohibited by law, taxed, or restricted. Patients, pharmacists, and prescribers cannot seek reimbursement from health insurance or any third party for any part of the benefit received by the patient through this offer. RedHill Biopharma reserves the right to rescind, revoke, or amend this offer, eligibility, and terms of use at any time without notice. This offer is not conditioned on any past, present, or future purchase, including refills. Offer must be presented along with a valid prescription for MOVANTIK® (naloxegol) tablets at the time of purchase.

BY USING THIS CARD, YOU AND YOUR PHARMACIST UNDERSTAND AND AGREE TO COMPLY WITH THESE ELIGIBILITY REQUIREMENTS AND TERMS OF USE.

Program managed by ConnectiveRx on behalf of RedHill Biopharma Ltd.

References: 1. Coyne KS, LoCasale RJ, Datto CJ, Sexton CC, Yeomans K, Tack J. Opioid-induced constipation in patients with chronic noncancer pain in the USA, Canada, Germany, and the UK: descriptive analysis of baseline patient-reported outcomes and retrospective chart review. Clinicoecon Outcomes Res. 2014;6:269-281. 2. Panchal SJ, Müller-Schwefe P, Wurzelmann JI. Opioid-induced bowel dysfunction: prevalence, pathophysiology and burden. Int J Clin Pract. 2007;61:1181-1187. 3. Becker G, Blum HE. Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus. Lancet. 2009;373:1198-1206. 4. Brock C, Olesen SS, Olesen AE, Frøkjaer JB, Andresen T, Drewes AM. Opioid-induced bowel dysfunction: pathophysiology and management. Drugs. 2012;72:1847-1865. 5. MOVANTIK® (naloxegol). Prescribing information. RedHill Biopharma Inc; 2020. 6. Data on file. Managed Markets Insight & Technology coverage data. RedHill Biopharma Inc; June 2020. 7. CVS Pharmacy. Accessed November 3, 2020. https://www.cvs.com/shop
IMPORTANT SAFETY INFORMATION ABOUT MOVANTIK
  • MOVANTIK may cause serious side effects, including:
    • Opioid withdrawal. You may have symptoms of opioid withdrawal during treatment with MOVANTIK, including sweating, chills, diarrhea, stomach pain, anxiety, irritability, and yawning. Patients taking methadone to treat their pain may be more likely to experience stomach pain and diarrhea. Tell your doctor if you have any of these symptoms
    • Severe Stomach Pain and/or Diarrhea. This can happen within a few days of starting MOVANTIK and can lead to hospitalization. If either of these side effects occurs, stop taking MOVANTIK and call your doctor immediately
    • Tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you get stomach pain that gets worse or does not go away, stop taking MOVANTIK and get emergency medical help right away
  • Do not take MOVANTIK if you:
    • Have a bowel blockage (intestinal obstruction) or have a history of bowel blockage
    • Are allergic to MOVANTIK or any of the ingredients in MOVANTIK
  • MOVANTIK can interact with other medicines and cause side effects, including opioid withdrawal symptoms (see symptoms above). Tell your doctor or pharmacist before you start or stop any medicines during treatment with MOVANTIK
  • Before you take MOVANTIK, tell your doctor about all of your medical conditions, including if you:
    • Have any stomach, bowel (intestines) problems, including inflammation in parts of the large intestine (diverticulitis), or inflammation and injury of the intestines caused by reduced blood flow (ischemic colitis)
    • Have had recent surgery on the stomach or intestines
    • Have any kidney, or liver problems
    • Are pregnant or plan to become pregnant. Taking MOVANTIK during pregnancy may cause opioid withdrawal symptoms in you or your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with MOVANTIK
    • Are breastfeeding or plan to breastfeed. It is not known if MOVANTIK passes into your breast milk. Taking MOVANTIK while you are breastfeeding may cause opioid withdrawal in your baby. You and your healthcare provider should decide if you will take MOVANTIK or breastfeed. You should not breastfeed if you take MOVANTIK
  • Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect the way MOVANTIK works
  • If you stop taking your opioid pain medicine, stop taking MOVANTIK and tell your doctor
  • Avoid eating grapefruit or drinking grapefruit juice during treatment with MOVANTIK
  • The most common side effects of MOVANTIK include: Stomach (abdomen) pain, diarrhea, nausea, gas, vomiting, headache, and excessive sweating
APPROVED USE FOR MOVANTIK

MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.

Click here for the Medication Guide and full Prescribing Information for MOVANTIK.

You are encouraged to report Adverse Reactions to RedHill Biopharma Inc. at 1-833-ADRHILL (1-833-237-4455) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

RedHill Biopharma Inc. supports the responsible use of medications, including those containing opioids, as treatment options for patients with chronic non-cancer pain.

This site is intended for US Consumers only.

The information on this website should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about MOVANTIK, or about constipation caused by opioid use for chronic non-cancer pain, talk to your doctor or pharmacist. Only you and your doctor can decide if MOVANTIK is right for you.

RedHill Biopharma Inc. (U.S. Office)
8045 Arco Corporate Drive, Suite 200
Raleigh, NC 27617
Tel: +1-984-444-7010
Fax: +1-919-406-0400
info@redhillus.com

The information on the following site is intended for US health care professionals. Please choose:

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Think you have opioid-induced constipation?

Think you have opioid-induced constipation?

Begin the quiz

Are you currently taking any opioid pain medication(s) for chronic non-cancer pain?

Select one

Yes
No
Not sure
Submit

MOVANTIK is meant for people taking opioids in order to treat opioid-induced constipation in adults with chronic non-cancer pain.

If you’re experiencing constipation, talk to your doctor about your options for treatment.2,3

Go back

How many bowel movements do you have per week?

Select one

≤1
2-3
4 or more
Submit

MOVANTIK is for the treatment of opioid-induced constipation in adults with chronic non-cancer pain. Having less than 3 bowel movements per week while taking opioids can be a symptom of opioid-induced constipation.

If you’re experiencing constipation, talk to your doctor
about your options for treatment.2,3

Go back

When completing a bowel movement, have you experienced any of the following?

Select all that apply

Straining
Hard or lumpy
stools
Sense of incomplete evacuation
Submit

You may have opioid-induced constipation.1-3

Talk to you doctor about your symptoms and learn how
MOVANTIK may be able to help.

References: 1. Brock C, Olesen SS, Olesen AE, Frøkjaer JB, Andresen T, Drewes AM. Opioid-induced bowel dysfunction: pathophysiology and management. Drugs. 2012;72:1847-1865. 2. MOVANTIK® (naloxegol). Prescribing information. RedHill Biopharma Inc; 2020. 3. Chey WD, Webster L, Sostek M, Lappalainen J, Barker PN, Tack J. Naloxegol for opioid-induced constipation in patients with noncancer pain. N Engl J Med. 2014;370:2387-2396.