Prescribing Information
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When opioid constipation slows you down,

MOVANTIK gets you moving.

Number 1 Prescribed Oral Treatment of its kind

If you’re taking opioids and are constipated, don’t suffer in silence.

Find out if MOVANTIK
is right for you
Same-day relief is possible.
Find out how
Save with MOVANTIK
References: 1. MOVANTIK® (naloxegol). Prescribing information. Valinor Pharma, LLC; 2023. 2. Data on file. Prescription data. Valinor Pharma, LLC; 2023.
APPROVED USE FOR MOVANTIK

MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.

IMPORTANT SAFETY INFORMATION ABOUT MOVANTIK
  • MOVANTIK may cause serious side effects, including:
    • Opioid withdrawal. You may have symptoms of opioid withdrawal during treatment with MOVANTIK, including sweating, chills, diarrhea, stomach pain, anxiety, irritability, and yawning. If you take methadone to treat your pain, you may be more likely to have stomach pain and diarrhea than people who do not take methadone. Tell your healthcare provider if you have any of these symptoms
    • Severe stomach (abdominal) pain and/or diarrhea. Severe stomach pain and diarrhea can happen when you take MOVANTIK. These problems can happen within a few days after you start taking MOVANTIK and can lead to hospitalization. Stop taking MOVANTIK and call your healthcare provider right away if you have severe stomach pain or diarrhea, or both severe stomach pain and diarrhea
    • Tear in your stomach or intestinal wall (perforation). Stomach pain that is severe can be a sign of a serious medical condition. If you get stomach pain that gets worse or does not go away, stop taking MOVANTIK and get emergency medical help right away
  • Do not take MOVANTIK if you:
    • Have a bowel blockage (intestinal obstruction) or have a history of bowel blockage
    • Are allergic to MOVANTIK or any of the ingredients in MOVANTIK
  • MOVANTIK can interact with certain other medicines and cause side effects, including opioid withdrawal symptoms such as sweating, chills, diarrhea, stomach pain, anxiety, irritability, and yawning. Tell your healthcare provider or pharmacist before you start or stop any medicines during treatment with MOVANTIK
  • Before you take MOVANTIK, tell your doctor about all of your medical conditions, including if you:
    • Have any stomach or bowel (intestines) problems, including inflammation in parts of the large intestine (diverticulitis), or inflammation and injury of the intestines caused by reduced blood flow (ischemic colitis), or cancer of the stomach or bowel
    • Have had recent surgery on the stomach or intestines
    • Have any kidney or liver problems
    • Are pregnant or plan to become pregnant. Taking MOVANTIK during pregnancy may cause opioid withdrawal symptoms in you or your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with MOVANTIK
    • Are breastfeeding or plan to breastfeed. It is not known if MOVANTIK passes into your breast milk. Taking MOVANTIK while you are breastfeeding may cause opioid withdrawal in your baby. You and your healthcare provider should decide if you will take MOVANTIK or breastfeed. You should not breastfeed if you take MOVANTIK
  • Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect the way MOVANTIK works
  • Especially tell your healthcare provider if you take a medicine called bevacizumab
  • Tell your healthcare provider if you stop taking your opioid pain medicine. If you stop taking your opioid pain medicine, you should also stop taking MOVANTIK
  • Avoid eating grapefruit or drinking grapefruit juice during treatment with MOVANTIK
  • The most common side effects of MOVANTIK include: stomach (abdomen) pain, diarrhea, nausea, gas, vomiting, headache, and excessive sweating. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of MOVANTIK
  • It is not known if MOVANTIK is safe and effective in children

You may report side effects to Valinor Pharma at 1-877-592-2337 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Click here for the Medication Guide and full Prescribing Information for MOVANTIK.

Valinor Pharma, LLC, supports the responsible use of medications, including those containing opioids, as treatment options for patients with chronic non-cancer pain.

This site is intended for US Consumers only.

The information on this website should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about MOVANTIK, or about constipation caused by opioid use for chronic non-cancer pain, talk to your doctor or pharmacist. Only you and your doctor can decide if MOVANTIK is right for you.

The information on the following site is intended for US healthcare professionals. Please choose:

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Think you have opioid-induced constipation?

Think you have opioid-induced constipation?

Begin the quiz

Are you currently taking any opioid pain medication(s) for chronic non-cancer pain?

Select one

Yes
No
Not sure
Submit

MOVANTIK is meant for people taking opioids in order to treat opioid-induced constipation in adults with chronic non-cancer pain.

If you’re experiencing constipation, talk to your doctor about your options for treatment.2,3

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How many bowel movements do you have per week?

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≤1
2-3
4 or more
Submit

MOVANTIK is for the treatment of opioid-induced constipation in adults with chronic non-cancer pain. Having less than 3 bowel movements per week while taking opioids can be a symptom of opioid-induced constipation.

If you’re experiencing constipation, talk to your doctor
about your options for treatment.2,3

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When completing a bowel movement, have you experienced any of the following?

Select all that apply

Straining
Hard or lumpy
stools
Sense of incomplete evacuation
Submit

You may have opioid-induced constipation.1-3

Talk to you doctor about your symptoms and learn how
MOVANTIK may be able to help.

References: 1. Brock C, Olesen SS, Olesen AE, Frøkjaer JB, Andresen T, Drewes AM. Opioid-induced bowel dysfunction: pathophysiology and management. Drugs. 2012;72:1847-1865. 2. MOVANTIK® (naloxegol). Prescribing information. Valinor Pharma, LLC; 2023. 3. Chey WD, Webster L, Sostek M, Lappalainen J, Barker PN, Tack J. Naloxegol for opioid-induced constipation in patients with noncancer pain. N Engl J Med. 2014;370:2387-2396.

Coverage for the #1 prescribed oral
PAMORA just got even better1

*Data as of June 2021.3

Plans and coverage may vary and are subject to change. General information only, not a guarantee of coverage. Coverage and status do not imply efficacy or safety.

PAMORA=peripherally acting mu-opioid receptor antagonist; PDP=prescription drug plan.

References: 1. Data on file. Prescription data. Valinor Pharma, LLC; 2023. 2. Data on file. Prime Therapeutics formulary coverage. Valinor Pharma, LLC; 2023. 3. Data on file. Cigna formulary coverage. Valinor Pharma, LLC; 2023.

SELECT IMPORTANT SAFETY INFORMATION ABOUT MOVANTIK

  • MOVANTIK® (naloxegol) is contraindicated in:
    • Patients with known or suspected gastrointestinal (GI) obstruction and patients at risk of recurrent obstruction, due to the potential for GI perforation
    • Patients receiving strong CYP3A4 inhibitors (eg, clarithromycin, ketoconazole) because these medications can significantly increase exposure to naloxegol which may precipitate opioid withdrawal symptoms

Click here for additional Important Safety Information and full Prescribing Information for MOVANTIK.